Do you get diarrhea with multiple myeloma?
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Do you get diarrhea with multiple myeloma?
Background: One of the most common and inadequately managed symptoms that patients with multiple myeloma (MM) experience as a result of cancer treatment is diarrhea. Diarrhea in patients with MM often is severe enough to warrant dose reduction, delays, or discontinuation of chemotherapy.
Can multiple myeloma cause digestive issues?
The cancerous plasma cells are called myeloma cells. may be associated with gastrointestinal problems (e.g., nausea, vomiting, diarrhea, and constipation). Do not stop or adjust medications without discussing it with your healthcare provider.
What are the symptoms of Plasmacytoma?
Extramedullary plasmacytoma
- Swelling or a mass.
- Headache.
- Nasal discharge, nose bleeds, nasal obstruction.
- Sore throat, hoarseness, difficulty talking (dysphonia)
- Difficulty swallowing (dysphagia), stomach pain.
- Breathlessness (dyspnoea), coughing up blood (haemoptysis)
Can myeloma cause bowel problems?
Gastrointestinal (GI) disturbances are issues involving your stomach and intestines. This can include nausea, vomiting, constipation and diarrhoea. These are very common side effects in myeloma patients, and can upset normal day-to-day life and be distressing to live with.
Does multiple myeloma cause leg pain?
Nerve damage: Myeloma proteins can be toxic to your nerves. This can lead to a condition called peripheral neuropathy that causes a pins-and-needles feeling, often in your legs and feet.
What are the causes and treatment of plasmacytoma?
Plasmacytoma causes It is not known what causes plasmacytoma. Radiation, industrial solvents and airborne toxins have been identified as possible risk factors. Factors such as viral pathogenesis and irritation from inhaled irritants have been noted.
How long does it take plasmacytoma to develop to multiple myeloma?
The median time to progression of plasmacytoma to multiple myeloma is 2-3 years, with progression more likely to occur in solitary bone plasmacytoma than extramedullary plasmacytoma 5).
Why is plasmacytoma more common in men than in women?
Plasmacytoma mainly affects people in the 5th to 6th decade of their lives, and the incidence of the disease is higher in men than in women 3). Incidence rates anywhere from 2 to 3 times higher in men than in women have been reported 4).
Where does plasmacytoma occur in the bone marrow?
Plasmacytoma can be present as a discreet solitary mass of abnormal monoclonal plasma cells (solitary plasmacytoma) that occurs either inside the bone marrow, in which case it is termed a solitary bone plasmacytoma or outside bone marrow where it’s called extramedullary plasmacytoma.