What is pentoxifylline used for?

Pentoxifylline improves the flow of blood through blood vessels. It is used to reduce leg pain caused by poor blood circulation. Pentoxifylline makes it possible to walk farther before having to rest because of leg cramps.

What are side effects associated with using pentoxifylline?

What Are Side Effects Associated with Using Pentoxifylline?

• nausea.
• vomiting.
• gas.
• bloating.
• belching.
• upset stomach.
• diarrhea.
• dizziness.

When should you take pentoxifylline?

Swallow the tablet whole. Do not crush, break, or chew it before swallowing. Pentoxifylline should be taken with meals to lessen the chance of stomach upset.

How safe is pentoxifylline?

Overall, pentoxifylline is a very safe drug and is usually well tolerated. The side-effects are dose-related and the most common are those of the gastrointestinal tract and central nervous system. The main central nervous system side effects are dizziness, headache, anxiety and confusion.

Is pentoxifylline a painkiller?

Pentoxifylline can decrease the muscle aching/pain/cramps during exercise, including walking, that occur with intermittent claudication. Pentoxifylline belongs to a class of drugs known as hemorrheologic agents. It works by helping blood flow more easily through narrowed arteries.

Can pentoxifylline cause high blood pressure?

Pentoxifylline did not alter blood pressure or plasma IL-6 concentration but did significantly decrease circulating TNF-α and C-reactive protein (CRP) concentrations, a study in the Journal of Hypertension reported.

How quickly does pentoxifylline work?

Although you may feel the effects of this medication in 2-4 weeks, you may need to take it for up to 8 weeks before you feel the full effect of pentoxifylline. Pentoxifylline controls the symptoms of circulation problems, but does not cure them. Continue to take pentoxifylline even if you feel well.

Does pentoxifylline lower BP?

Does pentoxifylline make you tired?

Central nervous system: Drowsiness/sleepiness, tremor, agitation anxiety, confusion, insomnia, restlessness. Gastrointestinal: Abdominal burning, abdominal pain, anorexia flatus, constipation, haemorrhage, heartburn, salivation, dry mouth/throat, hepatitis, jaundice, increased liver enzymes.

Does pentoxifylline thin the blood?

It works by helping blood flow more easily through narrowed arteries. This increases the amount of oxygen that can be delivered by the blood when the muscles need more (such as during exercise) thereby increasing walking distance and duration.

Is pentoxifylline a muscle relaxer?

What drugs increase blood flow?

Pentoxifylline is used to improve blood flow in patients with circulation problems to reduce aching, cramping, and tiredness in the hands and feet. It works by decreasing the thickness (viscosity) of blood. This change allows your blood to flow more easily, especially in the small blood vessels of the hands and feet.

What are the active ingredients in pentoxifylline tablets?

TRENTAL (pentoxifylline) tablets for oral administration contain 400 mg of the active drug and the following inactive ingredients: FD&C Red No. 3, hypromellose USP, magnesium stearate NF, polyethylene glycol NF, povidone USP, talc USP, titanium dioxide USP, and hydroxyethyl cellulose USP in an extended-release formulation.

Is it OK to chew pentoxifylline 400mg tablets?

Product Summary. Do not crush or chew this medication. Doing so can release all of the drug at once, increasing the risk of side effects. Also, do not split the tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet without crushing or chewing.

Which is better crushed or intact pentoxifylline tablets?

Intact 400-mg extended-release pentoxifylline tablets, crushed 400-mg tablets, intact 600-mg tablets, and crushed 600-mg tablets were given sequentially to 10 healthy … The pharmacokinetics of crushed and intact pentoxifylline tablets were compared, and the frequency of adverse effects was evaluated.

Are there any serious side effects from pentoxifylline?

Pentoxifylline has no known severe interactions with other drugs. Pentoxifylline has no known serious interactions with other drugs. Moderate interactions of pentoxifylline include: amidarone. benazepril. captopril. cimetidine.