Which is worse MSA P or MSA C?

Several predictive factors for the progression and survival prognosis of those with MSA have been proposed. Patients with MSA-P show a more rapid disease progression and survive for a shorter time than patients with MSA-C. Furthermore, the early development of motor and autonomic dysfunctions results in poor prognosis.

Is MSA always fatal?

People typically live about seven to 10 years after multiple system atrophy symptoms first appear. However, the survival rate with MSA varies widely. Occasionally, people can live for 15 years or longer with the disease. Death is often due to respiratory problems.

Can a MSA patient have complete airway obstruction?

In one instance, a MSA patient developed complete upper airway obstruction upon being anesthetized in preparation for microlaryngoscopy, an imaging procedure that involves passing a tube with a video camera into the throat17.

Why do people with MSA-C look intoxicated?

As a result of the disease, people with MSA-C have difficulty coordinating walking, hand movements, speech, and eye movements. Sometimes they look intoxicated without having had an alcoholic beverage, so it can be useful to carry a medical card should anyone ask.

How are breathing disorders related to multiple system atrophy?

Disorders affecting breathing are common in patients with MSA and may arise from atrophy or overactivation of breathing or vocal cord muscles or a combination of the two, as well as degeneration in areas of the brain that control respiration. In one type of breathing disorder, known as stridor, a characteristic wheezing sound occurs when inhaling.

What are the two main subtypes of MSA?

MSA is broken down into two main subtypes based on the predominant symptom: MSA-predominant Parkinsonism (MSA-P), and MSA-predominant cerebellar ataxia (MSA-C). A patient diagnosed with MSA-P may over time appear to have MSA-C and vice versa, so these categorizations are not always set in stone.