What drugs should be avoided in G6PD?


What drugs should be avoided in G6PD?

The following is a partial list of medications and chemicals that individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency should avoid:

  • Acetanilid.
  • Furazolidone.
  • Isobutyl nitrite.
  • Nalidixic acid.
  • Naphthalene.
  • Niridazole.
  • Sulfa drugs.

Which drug caused hemolysis in G6PD deficient patients?

Antimalarial medicines such as quinine. Aspirin (high doses) Nonsteroidal anti-inflammatory drugs (NSAIDs) Quinidine.

Does G6PD cause intravascular hemolysis?

In persons with G6PD deficiency, oxidative stresses can denature hemoglobin and cause intravascular hemolysis.

Which medication would you avoid in a patient with a G6PD deficiency due to risk for hemolytic anemia?

Malaria Medications Primaquine is a medicine used to treat or prevent malaria. But it can also trigger a hemolytic crisis in people with G6PD deficiency. 2 A hemolytic crisis is when your body destroys red blood cells faster than it can make new ones.

What food should avoid if you have G6PD?

Your child should not eat fava beans. Some people should also avoid red wine, all beans, blueberries, soya products, tonic water and camphor.

Can G6PD take vitamin C?

Vitamin C has been categorised as “probably safe” in “normal therapeutic doses” in G6PD deficiency.

Is Vitamin C Not Good for G6PD?

Is vitamin C contraindicated in G6PD?

These data suggest that in the dosage currently under investigation (6 g/day), vitamin C should not be considered contraindicated in patients with known or suspected G6PD deficiency. This is important, as GDPD deficiency is not uncommon in patients of African and Mediterranean descent [5].

How does G6PD deficiency cause hemolytic anemia?

Factors such as infections, certain drugs, or eating fava beans can increase the levels of reactive oxygen species, causing red blood cells to be destroyed faster than the body can replace them. This reduction of red blood cells causes the signs and symptoms of hemolytic anemia in people with G6PD deficiency.

Which is the most common medical problem associated with G6PD deficiency?

The most common medical problem associated with glucose-6-phosphate dehydrogenase deficiency (G6PD deficiency) is hemolytic anemia, which occurs when red blood cells are destroyed faster than the body can replace them.

When do you need a transfusion for G6PD deficiency?

The most important aspect of management for G6PD deficiency is to avoid agents that might trigger an attack. In cases of acute hemolytic anemia, a blood transfusion or even an exchange transfusion may be required.

When to test for G6PD deficiency in children?

Testing should be considered in children and adults (especially males of African, Mediterranean, or Asian descent) with an acute hemolytic reaction caused by infection, exposure to a known oxidative drug, or ingestion of fava beans.